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Drug intelligence / Profile preview
[64Cu]Cu-NODAGA-galacto-BBN
- Development stage
- Preclinical
- Lead developer
- Korea Institute of Radiological and Medical Sciences
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Beta-minus Emitters → Radiopharmaceuticals, Positron Emitters → Radiopharmaceuticals
01
Overview
[64Cu]Cu-NODAGA-galacto-BBN: sourced facts only. name: "We confirmed that [64Cu]Cu-NODAGA-galacto-BBN targets GRPR in irradiated RAW 264.7 cells." [PMID:36542354]; target: "We confirmed that [64Cu]Cu-NODAGA-galacto-BBN targets GRPR in irradiated RAW 264.7 cells." [PMID:36542354]; developer: "Division of Applied RI, Korea Institute of Radiological and Medical Sciences, Seoul 01812, South Korea." [PMID:36542354]; modality: "Previously, our group synthesized a GRPR-targeted positron emission tomography (PET) imaging probe, [64Cu]Cu-NODAGA-galacto-bombesin (BBN), an analogue peptide of GRP." [PMID:36542354]; stage: "Furthermore, [64Cu]Cu-NODAGA-galacto-BBN could monitor the therapeutic efficacy of pirfenidone in RIPF mice." [PMID:36542354]
02
Targets
GRPR (Gastrin-releasing peptide receptor)
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